10x Genomics Unveils Chromium Xo: A Low-Cost Instrument to Expand Access to High-Performance Single Cell Research

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PLEASANTON, Calif., Sept. 3, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, today announced the launch of Chromium Xo, a new addition to its fleet of Chromium single cell instruments. Designed to meet the needs of researchers who desire high-quality data on limited budgets, Chromium Xo offers an affordable entry point into routine, high-performance single cell analysis.

10x Genomics Logo (PRNewsfoto/10x Genomics, Inc.)

"Chromium Xo is the latest in a series of 10x innovations intended to democratize single cell analysis because we never want researchers to have to settle for anything less than the best," said Ben Hindson, Chief Scientific Officer and Co-founder. "With Chromium Xo, we're not just lowering the cost barrier; we're empowering more researchers to achieve high-quality, repeatable results necessary for meaningful scientific breakthroughs."

Chromium Xo is 10x Genomics' most affordable single cell instrument, delivering the high-quality data, superior reproducibility and ease of use that the company's instrument-powered workflows are known for, at a U.S. list price of $25,000.

Chromium Xo is specifically designed to run 10x Genomics' industry-leading GEM-X 3' assay, which provides up to 80% cell capture and more than 40% higher gene sensitivity compared to alternative non-10x methods. GEM-X technology also enables researchers to generate more usable reads to detect more genes with less sequencing, potentially saving more than 50% on sequencing costs compared to non-10x methods.

In addition, there is a path for researchers to seamlessly upgrade to Chromium X to access the full breadth of the company's single cell portfolio, including assays for FFPE samples and immune profiling.

With features like automation to partition hundreds of thousands of cells in minutes and an intuitive push-button interface for efficient cell processing, Chromium instruments remove many of the challenges and inconsistencies of manual, instrument-less workflows. The instrument-powered Chromium platform enables high data quality and twice the sample recovery as manual methods. In addition, Chromium instruments streamline the workflow, improve scalability and enable superior reproducibility, resulting in less hands-on time, lower labor and experimental costs and faster time to results compared to alternative single cell workflows.

Added Hindson, "Our ultimate goal is to enable high-performance single cell analysis for $100 per sample. With Chromium Xo and what's planned in our pipeline, we are continuing to drive our Chromium technology in that direction so more researchers can rely on these methods more often."